Ankylosing spondylitis is a disease that primarily affects the spine. In this condition, the joints and ligaments that allow the spine to move become inflamed and stiff. This disease can also affect other joints in the body. In some cases, the disease can even affect the heart or other organs. A physician will use symptoms and X-rays to make a diagnosis of the condition.
Medication can be effective for treating ankylosing spondylitis. Non-steroidal anti-inflammatory drugs such as ibuprofen and paracetamol may help alleviate the pain and stiffness of ankylosing spondylitis. There are also steroid injections that can help control the inflammation.
Ankylosing spondylitis is a progressive type of arthritis that primarily affects the joints and bones of the spine. In severe cases, the disease can cause the spine to fuse and cause severe pain. Patients with this condition should take painkillers and exercise regularly to keep their back strong.
Although ankylosing spondylitis can affect your life, it is not uncommon for sufferers to still continue a full and productive life. Depending on the severity of the disease, doctors may prescribe TNF inhibitors, which block the inflammation. If this is not effective, a person may need to seek help from other health professionals, such as occupational therapists or physical therapists. A good partner between the patient and the health care provider is essential to treatment success.
The symptoms of ankylosing spondylitis typically begin around the sacroiliac joints. They may spread to other areas of the spine. Symptoms usually worsen during periods of inactivity and improve with movement. The treatment for ankylosing spondylitis includes non-steroidal anti-inflammatory drugs and immune suppressing medicines.
A blood test and a pain score can help doctors diagnose ankylosing spondylitis. Patients may also be given a test to determine whether they carry the HLA-B27 gene. This gene can be found in 90 percent of people with the disease. Treatment for ankylosing spondylitis aims to reduce pain, prevent deformities, and maintain normal activity levels.
If a patient fails to find relief from the symptoms, treatment options may include joint replacement surgery. In some cases, this procedure can be successful and restore joint function. The surgery may also help reduce the symptoms of ankylosing spondylitis. It’s a good option for some people, but it’s important to consult a qualified surgeon if this is the only treatment option.
The first symptom of AS is inflammation of the sacroiliac joints, which connect the pelvis and spine. Inflammation of these joints causes calcium deposits to form in the ligaments of the spine. This builds up over time, which results in restricted movement. Eventually, the calcified ligaments may fuse the vertebrae.
The underlying pathogenesis of ankylosing spondylitis is complex. Several hypotheses have been proposed to explain its occurrence. One of these is the overexpression of ERAP1 and ERAP2, which are both involved in the development of AS. However, there are other related genes and factors that may influence the pathogenesis of AS.